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| Section | Objectives |
|---|---|
| SAS Programming for Clinical Trials | - Data Management
|
| Regulatory and Clinical Research Concepts | - Clinical trial workflow
|
| Clinical Trials Data Standards | - CDISC Standards
|
1. Which name is a valid SAS V5 variable name?
A) AE_START_DTC
B) AE-STDTC
C) AESTARTDTC
D) _AESTDTC
2. What is the primary purpose for specifying identifier variables across SDTM domains?
A) To uniquely reference each record
B) To include the appropriate subject information
C) To include the appropriate study information
D) To satisfy regulatory conditions
3. In a Statistical Analysis Plan (SAP) the following statement is written:
To test the association between the pain intensity reported by the patient and the treatment the patient has been administered, a Cochran-Mantel-Haenszel test will be performed adjusting for the country of the patient's investigational site.
The following variables and levels are used:
- Pain intensity (PAIN): "No pain", "Mild pain", "Moderate pain", "Severe pain", "Most severe pain"
- Treatment group (TREAT): "Placebo", "Drug A", "Drug B"
- Country (COUNTRY): Eight different values.
The following program is written to perform this analysis:
proc freq data=pain;
by COUNTRY;
tables PAIN * TREAT / cmh;
run;
This code does not produce the analysis requested by the SAP.
What is wrong with this code?
A) The variable COUNTRY should be on the TABLES statement instead of the BY statement.
B) The option CMH should be on the PROC FREQ statement instead of on the TABLES statement.
C) The variable PAIN should be on the BY statement along with the variable COUNTRY.
D) The variables PAIN and TREAT should be on the BY statement, and the variable COUNTRY should be on the TABLES statement.
4. Given the SAS data set containing subject's phone numbers
What is the value of PHONE2 for subject 005?
A) 2156319494
B) 631-9494
C) (215) 631-9494
D) (215) 6319494
5. Given the SAS data set WORK.BP
What is the result?
A) WORK.HIGHBP has 1 observation
WORK.NORMBP has 1 observation
WORK.INVESTBP has 2 observations
B) WORK.HIGHBP has 1 observation
WORK.NORMBP has 1 observation
WORK.INVESTBP has 4 observations
C) WORK.HIGHBP has 2 observations
WORK.NORMBP has 2 observations
WORK.INVESTBP has 3 observations
D) WORK.HIGHBP has 1 observation
WORK.NORMBP has 1 observation
WORK.INVESTBP has 3 observations
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: A | Question # 3 Answer: A | Question # 4 Answer: A | Question # 5 Answer: B |
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